Synonym: DENV NS1 antigen
Species: Dengue virus
Protein Accession: P33478
Purity: Greater than 90%
Endotoxin Level: Less than 1 EU/ug
Biological Activity: Functional assay
Expression System: Mammalian cells
Fusion Tag: None
Predicted Molecular Mass: 45 kDa
Formulation: Lyophilized
Reconstitution: Dissolve in sterile water
Storage & Stability: Store at -20°C upon arrival, stable for 3 months from the
date of shipment
FAQ
**What are the primary raw materials of the Dengue virus that can be beneficial in the
feed industry?**
The primary raw materials of the Dengue virus that can be
utilized in the feed industry include viral proteins, whole inactivated viruses, and RNA
fragments. These components can be harnessed to develop immune-boosting feed additives.
Viral proteins, like NS1, can stimulate the immune system in animals, enhancing their
resistance to various pathogens. Whole inactivated viruses serve as potent immunogens
and can be used to create vaccines or feed additives that prime the immune system. RNA
fragments can activate innate immunity via toll-like receptors, amplifying the animal's
natural defense mechanisms. Utilizing these components not only improves overall animal
health but also reduces the need for antibiotics, leading to more sustainable farming
practices.
**How can viral proteins derived from Dengue virus be incorporated
into animal feed?**
Viral proteins from Dengue virus can be processed and
incorporated into animal feed in various ways. One approach is through encapsulation in
liposomes or nanoparticles, which protect the proteins from degradation in the
gastrointestinal tract and ensure a controlled release. Alternatively, viral proteins
can be adsorbed onto feed ingredients or mixed into feed premixes. It’s crucial to
ensure that the viral proteins are inactivated adequately to prevent any potential
pathogenic effects while retaining their immunogenic properties. Feed manufacturers can
employ current biotechnological techniques to integrate these proteins into the feed,
ensuring uniform distribution and stability. By incorporating viral proteins, the feed
can act as an oral immunostimulant, enhancing the animals' immunity.
**Are there
any safety concerns related to using Dengue virus raw materials in animal
feed?**
Safety concerns regarding the use of Dengue virus raw materials in animal
feed primarily revolve around ensuring that the materials are properly inactivated to
eliminate any infectious potential. Regulatory approval and thorough testing are crucial
steps to ensure the safety of these substances. Inactivation methods like heat
treatment, chemical inactivation, or irradiation must be employed to neutralize the
virus effectively while maintaining its immunogenic properties. Additionally, it is
essential to monitor for any potential allergic reactions in animals and ensure that the
introduction of these materials does not inadvertently affect the nutritional balance of
the feed. Proper documentation, adherence to safety protocols, and conducting
comprehensive trials will mitigate these concerns and ensure that the feed additives are
safe for consumption.
**What are the benefits of including Dengue virus raw
materials in livestock feed?**
Incorporating Dengue virus raw materials into
livestock feed offers several benefits. Primarily, these materials act as
immunostimulants, enhancing the animals' innate and adaptive immune responses. This
leads to improved resistance against various diseases, reducing reliance on antibiotics
and promoting overall herd health. Enhanced immunity translates to better growth rates
and productivity, as animals are less likely to fall ill. Additionally, the use of these
viral components can lead to more sustainable farming practices by decreasing the
environmental impact of antibiotic residues. Economic benefits also emerge from reduced
veterinary costs and increased productivity, making it an attractive option for farmers.
Overall, these feed additives support healthier livestock and more efficient farming
operations.
**How does the inclusion of RNA fragments from the Dengue virus in
animal feed affect animal health?**
RNA fragments from the Dengue virus, when
included in animal feed, can trigger the activation of the innate immune system. These
RNA fragments can mimic viral attacks, stimulating toll-like receptors (TLRs) in the
animals, which are critical for recognizing pathogens and activating immune responses.
This heightened state of immune readiness can make animals more resilient to infections
by enhancing their capacity to respond to various pathogens swiftly. Moreover, improved
immune function supports better metabolic health and overall well-being, leading to
enhanced growth and productivity. Continuous exposure to these RNA fragments can train
the immune system to react more effectively, thus promoting a stronger, more capable
livestock population that requires fewer medical interventions.