Synonym: Rotavirus VP6
Species: Rotavirus
Protein Accession: P0DTC9
Purity: Greater than 95% as determined by SDS-PAGE
Endotoxin Level: Less than 1.0 EU per μg of the protein
Biological Activity: Not specified
Expression System: Escherichia coli
Fusion Tag: None
Predicted Molecular Mass: 38 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl,
pH 8.0
Reconstitution: We recommend that this vial be briefly centrifuged prior to
opening to bring the contents to the bottom. Reconstitute in sterile distilled water or
aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions
should be made in appropriate buffered solutions.
Storage & Stability: Store at -20°C upon receipt, minimize freeze-thaw cycles.
FAQ
What are raw materials of rotavirus and their importance in the feed
industry?
Raw materials of rotavirus include antigens and purified protein
isolates derived from the rotavirus itself. These materials are essential in the feed
industry as they contribute to the development of vaccines and other preventive measures
against rotavirus infections, particularly in young livestock like calves and piglets.
These infections can lead to significant losses in animal productivity due to diarrhea
and other related illnesses. Ensuring that feed products include components derived from
raw materials of rotavirus helps in fortifying the immune systems of farm animals,
thereby reducing disease incidence, enhancing overall farm productivity, and maintaining
healthier livestock populations.
How do raw materials of rotavirus work in animal
feed formulations?
Incorporating raw materials of rotavirus into animal feed
works by inducing an adaptive immune response in the animals. When young livestock
consume feed that contains purified rotavirus antigens, their immune systems recognize
these proteins as foreign and mount an immune response. This process involves the
production of antibodies specific to the rotavirus, effectively equipping the animals
with the ability to fight off actual infections in the future. The strategic addition of
these materials into feed formulations ensures that livestock are better prepared to
handle exposure to the virus, thus reducing disease outbreaks and supporting better
growth and development.
Are there any specific livestock that benefit more from
rotavirus raw materials in their feed?
Yes, young livestock such as calves and
piglets benefit extensively from the inclusion of rotavirus raw materials in their feed.
These animals are particularly susceptible to rotavirus infections during the early
stages of their lives when their immune systems are still developing. The introduction
of these raw materials helps in preemptively strengthening their immune responses
against potential outbreaks. By protecting these young animals during their critical
growth phases, farmers can significantly decrease mortality rates, improve weight gain,
and ensure a healthier start, which translates to better overall farm productivity and
profitability.
How are raw materials of rotavirus sourced and ensure safety for
use in feed?
Sourcing raw materials of rotavirus involves isolating and purifying
specific antigens or protein isolates from the rotavirus pathogen. These processes are
carried out in controlled laboratory environments following stringent biosafety
protocols to ensure the materials are safe for use. The isolated antigens are then
subjected to rigorous quality control and testing to verify their purity, potency, and
safety before they are incorporated into feed products. This comprehensive process
ensures that these raw materials do not pose any risk of infection to the animals and
provide the intended immunological benefits effectively.
What considerations
should be taken into account when incorporating rotavirus raw materials into
feed?
When incorporating rotavirus raw materials into feed, several
considerations must be addressed to maximize their benefits. Firstly, it is essential to
determine the correct dosage and formulation to ensure that the antigens are present in
effective concentrations to induce an appropriate immune response. Additionally, the
stability of the antigens during feed processing and storage needs careful monitoring to
maintain their efficacy. Compatibility with other feed ingredients is also crucial to
avoid any adverse reactions. Finally, regular monitoring and evaluation of animal health
post-administration can help in fine-tuning the formulations to achieve optimal
outcomes, ensuring the feed industry can leverage these materials effectively to protect
livestock health.