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Raw Materials of Rotavirus

Synonym: Rotavirus VP6

Species: Rotavirus

Protein Accession: P0DTC9

Purity: Greater than 95% as determined by SDS-PAGE

Endotoxin Level: Less than 1.0 EU per μg of the protein

Biological Activity: Not specified

Expression System: Escherichia coli

Fusion Tag: None

Predicted Molecular Mass: 38 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.

Storage & Stability: Store at -20°C upon receipt, minimize freeze-thaw cycles.

FAQ

What are raw materials of rotavirus and their importance in the feed industry?

Raw materials of rotavirus include antigens and purified protein isolates derived from the rotavirus itself. These materials are essential in the feed industry as they contribute to the development of vaccines and other preventive measures against rotavirus infections, particularly in young livestock like calves and piglets. These infections can lead to significant losses in animal productivity due to diarrhea and other related illnesses. Ensuring that feed products include components derived from raw materials of rotavirus helps in fortifying the immune systems of farm animals, thereby reducing disease incidence, enhancing overall farm productivity, and maintaining healthier livestock populations.

How do raw materials of rotavirus work in animal feed formulations?

Incorporating raw materials of rotavirus into animal feed works by inducing an adaptive immune response in the animals. When young livestock consume feed that contains purified rotavirus antigens, their immune systems recognize these proteins as foreign and mount an immune response. This process involves the production of antibodies specific to the rotavirus, effectively equipping the animals with the ability to fight off actual infections in the future. The strategic addition of these materials into feed formulations ensures that livestock are better prepared to handle exposure to the virus, thus reducing disease outbreaks and supporting better growth and development.

Are there any specific livestock that benefit more from rotavirus raw materials in their feed?

Yes, young livestock such as calves and piglets benefit extensively from the inclusion of rotavirus raw materials in their feed. These animals are particularly susceptible to rotavirus infections during the early stages of their lives when their immune systems are still developing. The introduction of these raw materials helps in preemptively strengthening their immune responses against potential outbreaks. By protecting these young animals during their critical growth phases, farmers can significantly decrease mortality rates, improve weight gain, and ensure a healthier start, which translates to better overall farm productivity and profitability.

How are raw materials of rotavirus sourced and ensure safety for use in feed?

Sourcing raw materials of rotavirus involves isolating and purifying specific antigens or protein isolates from the rotavirus pathogen. These processes are carried out in controlled laboratory environments following stringent biosafety protocols to ensure the materials are safe for use. The isolated antigens are then subjected to rigorous quality control and testing to verify their purity, potency, and safety before they are incorporated into feed products. This comprehensive process ensures that these raw materials do not pose any risk of infection to the animals and provide the intended immunological benefits effectively.

What considerations should be taken into account when incorporating rotavirus raw materials into feed?

When incorporating rotavirus raw materials into feed, several considerations must be addressed to maximize their benefits. Firstly, it is essential to determine the correct dosage and formulation to ensure that the antigens are present in effective concentrations to induce an appropriate immune response. Additionally, the stability of the antigens during feed processing and storage needs careful monitoring to maintain their efficacy. Compatibility with other feed ingredients is also crucial to avoid any adverse reactions. Finally, regular monitoring and evaluation of animal health post-administration can help in fine-tuning the formulations to achieve optimal outcomes, ensuring the feed industry can leverage these materials effectively to protect livestock health.

Jiangsu East-Mab Biomedical Technology Co.,Ltd

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