Synonym: EPO
Species: Human
Protein Accession: P01588
Purity: ≥95%
Endotoxin Level:
<1.0 EU per μg of the protein
Biological Activity: The ED50 as determined by the dose-dependent
stimulation of the proliferation of human TF-1 cells is ≤0.1 ng/mL.
Expression System: E. coli
Fusion Tag: None
Predicted Molecular Mass: Approximately 34.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris,
500mM NaCl, pH 7.4
Reconstitution: We recommend that this vial can be briefly centrifuged
prior to opening to bring the contents to the bottom. Reconstitute in sterile
distilled water or aqueous buffer containing 0.1 % BSA to a concentration of
0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and
stored at ≤ -20°C.
Storage & Stability: Store at ≤ -20°C upon receipt, stable for up to 6
months after shipment when stored at ≤ -20°C.
FAQ
What is Y05801 Recombinant Human EPO and how does it benefit livestock in the
feed industry?
Y05801 Recombinant Human Erythropoietin (EPO) is a
synthetic protein that mimics the naturally occurring erythropoietin in the
body. It plays a pivotal role in regulating red blood cell production. In the
context of the feed industry, this recombinant form of EPO can be used to
enhance the health and productivity of livestock. For instance, livestock with
higher red blood cell counts exhibit improved oxygen delivery to tissues, which
in turn can lead to better growth rates, enhanced stamina, and superior overall
health. This eventually reflects positively on feed efficiency, as animals are
able to utilize nutrients more effectively. Additionally, in breeding programs,
the overall vigor and reproductive efficiency of livestock can be
improved.
How is Y05801 Recombinant Human EPO administered to livestock,
and what is the recommended dosage?
Y05801 Recombinant Human EPO is
typically administered via injection. The specific route and dosage vary
depending on the species, age, weight, and health status of the livestock.
Veterinarians often develop tailored administration plans to ensure optimal
dosage and effective results. It's vital to follow professional guidance when
dosing, as improper administration could lead to complications such as
polycythemia or other hematological imbalances. In general, for larger animals
like cattle, dosage might range from 50 IU/kg to 300 IU/kg administered
bi-weekly or as determined by a vet. When administered properly, the EPO
facilitates an increase in erythropoiesis without causing adverse side
effects.
Are there any potential side effects of using Y05801 Recombinant
Human EPO in livestock?
As with any bioactive substance, the use of
Y05801 Recombinant Human EPO in livestock carries potential side effects,
although these are generally rare. Most livestock respond well to treatment
without any significant issues. However, potential side effects could include
polycythemia (an excessive increase in red blood cell numbers), which can lead
to vascular complications if unchecked. Some animals may also exhibit an immune
response to the recombinant protein, potentially causing allergic reactions.
This is why veterinary monitoring and adherence to recommended dosages are
crucial. Additionally, there might be species-specific reactions that need
careful evaluation, emphasizing the importance of a customized approach by
veterinary professionals.
How does Y05801 Recombinant Human EPO compare
to other growth-promoting agents used in the feed industry?
Y05801
Recombinant Human EPO offers unique advantages compared to traditional
growth-promoting agents, such as hormonal growth promoters or antibiotics. While
many growth promoters operate through stimulating overall growth or enhancing
feed conversion, EPO works primarily through enhancing erythropoiesis, thus
improving the oxygen-carrying capacity of the blood. This can lead to natural
increases in stamina, endurance, and overall health, which are not typically
achieved by other growth agents. Unlike antibiotics, which can contribute to
resistance issues, or hormones that may face regulatory restrictions, EPO
represents a more biologically harmonious approach to enhancing livestock
productivity. However, it's imperative to weigh the benefits against potential
risks and costs, ensuring the choice aligns with production goals and ethical
considerations.
Is the use of Y05801 Recombinant Human EPO approved and
regulated for use in the feed industry?
The approval and regulation of
Y05801 Recombinant Human EPO for use in livestock vary by country and region. In
many jurisdictions, the use of bioengineered proteins like EPO in livestock is
tightly regulated to ensure food safety and animal welfare. Regulatory bodies
such as the FDA, EMA, or specific agricultural and veterinary boards review and
approve biotechnological agents for use in the feed industry. Livestock
producers should consult with veterinary professionals and adhere to local
regulations and guidelines to ensure compliance. The regulatory landscape is
always evolving, so staying informed about the latest approvals and restrictions
is essential for responsible and legal use.