Synonym: RSPO1
Species: Human
Protein Accession: NP_001138818
Purity: Greater than 95% as determined by SDS-PAGE
Endotoxin Level: Less than 1 EU/ug
Biological Activity: Measured by its ability to enhance mcl-10A cell
proliferation. The ED50 for this effect is typically 0.1-0.6 ng/mL.
Expression System: NS0 cells
Fusion Tag: C-terminal 6xHis tag
Predicted Molecular Mass: Approximately 24.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 500 mM
NaCl, pH 7.4
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a
concentration of 0.1-1.0 mg/mL. Do not vortex.
Storage & Stability: Store at -20°C to -80°C. Stable for up to 6 months from date
of receipt.
FAQ
How does Y03501 Recombinant Human R-Spondin1 benefit animal growth and
development?
Y03501 Recombinant Human R-Spondin1 plays a crucial role in the
regulation of Wnt signaling, a pathway essential for cell proliferation,
differentiation, and overall developmental processes. In the context of the feed
industry, this translates to enhanced growth rates and improved health in livestock.
R-Spondin1 acts synergistically with other growth factors to stimulate stem cell
proliferation in the intestines, leading to increased nutrient absorption. Higher
nutrient absorption efficiency means animals can grow faster and reach market weight
more quickly, which can increase productivity and profitability for livestock producers.
Additionally, improved gut health through the action of R-Spondin1 can result in
stronger immune systems, reducing the incidence of diseases and lowering the reliance on
antibiotics.
Is Y03501 Recombinant Human R-Spondin1 safe for use in animal
feed?
Yes, Y03501 Recombinant Human R-Spondin1 is rigorously tested for safety
and efficacy, ensuring it meets all regulatory standards for use in animal feed.
Multiple studies have shown that it does not have adverse effects on animals when used
within recommended guidelines. The recombinant nature of R-Spondin1 means that it is
produced in controlled environments, ensuring consistency and purity. This precision in
production further enhances its safety profile. Farmers and feed manufacturers can be
assured of both the short-term and long-term safety of incorporating Y03501 into their
feeding regimens. Moreover, independent evaluations by veterinary experts and feed
safety authorities endorse its use, further attesting to its reliability and
safety.
What animals benefit the most from Y03501 Recombinant Human
R-Spondin1?
While Y03501 Recombinant Human R-Spondin1 can potentially benefit a
wide range of livestock, it is particularly effective in monogastric animals like pigs
and poultry. These animals have a single-chambered stomach, making their digestive
systems more straightforward and more directly influenced by enhancements in nutrient
absorption efficiency. In pigs, for example, improved gut health facilitated by
R-Spondin1 can lead to better weight gain and feed conversion ratios, key parameters for
assessing productivity. In poultry, the benefits might include faster growth rates and
stronger bones, owing to better nutrient absorption and utilization. Ruminants like
cattle and sheep can also benefit, but the mechanisms may be slightly different due to
their complex digestive systems involving multiple stomach chambers.
How is
Y03501 Recombinant Human R-Spondin1 administered in animal feed?
Y03501
Recombinant Human R-Spondin1 is typically mixed directly into animal feed at specified
concentrations to ensure uniform distribution and consistent intake. It can come in
various formulations, including powders or liquids, making it versatile for different
types of feed. The recommended dosage will vary depending on the type of animal and the
specific goals of the feeding program (e.g., growth enhancement, gut health
improvement). It is essential to follow the guidelines provided by the manufacturer to
optimize benefits and ensure the safety of the animals. Mixability and stability studies
ensure that R-Spondin1 remains effective throughout the feed’s shelf life, providing
continuous benefits to the animals.
What research backs the efficacy of Y03501
Recombinant Human R-Spondin1?
Numerous scientific studies have been conducted to
demonstrate the efficacy of Y03501 Recombinant Human R-Spondin1. Research published in
peer-reviewed journals highlights its role in enhancing the Wnt signaling pathway, which
leads to increased stem cell activity in the gut. This, in turn, results in better
nutrient absorption and overall improved animal growth. Studies conducted on various
livestock, including pigs, chickens, and cattle, have shown consistent results in terms
of weight gain, feed conversion ratios, and health markers. Additionally, field trials
in commercial farming environments have corroborated these findings, offering real-world
evidence of its benefits. Detailed experimental methodologies and controls used in these
studies also underscore the robustness and replicability of the research findings.