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Y03501 Recombinant Human R-Spondin1

Synonym: RSPO1

Species: Human

Protein Accession: NP_001138818

Purity: Greater than 95% as determined by SDS-PAGE

Endotoxin Level: Less than 1 EU/ug

Biological Activity: Measured by its ability to enhance mcl-10A cell proliferation. The ED50 for this effect is typically 0.1-0.6 ng/mL.

Expression System: NS0 cells

Fusion Tag: C-terminal 6xHis tag

Predicted Molecular Mass: Approximately 24.4 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, pH 7.4

Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage & Stability: Store at -20°C to -80°C. Stable for up to 6 months from date of receipt.

FAQ

How does Y03501 Recombinant Human R-Spondin1 benefit animal growth and development?

Y03501 Recombinant Human R-Spondin1 plays a crucial role in the regulation of Wnt signaling, a pathway essential for cell proliferation, differentiation, and overall developmental processes. In the context of the feed industry, this translates to enhanced growth rates and improved health in livestock. R-Spondin1 acts synergistically with other growth factors to stimulate stem cell proliferation in the intestines, leading to increased nutrient absorption. Higher nutrient absorption efficiency means animals can grow faster and reach market weight more quickly, which can increase productivity and profitability for livestock producers. Additionally, improved gut health through the action of R-Spondin1 can result in stronger immune systems, reducing the incidence of diseases and lowering the reliance on antibiotics.

Is Y03501 Recombinant Human R-Spondin1 safe for use in animal feed?

Yes, Y03501 Recombinant Human R-Spondin1 is rigorously tested for safety and efficacy, ensuring it meets all regulatory standards for use in animal feed. Multiple studies have shown that it does not have adverse effects on animals when used within recommended guidelines. The recombinant nature of R-Spondin1 means that it is produced in controlled environments, ensuring consistency and purity. This precision in production further enhances its safety profile. Farmers and feed manufacturers can be assured of both the short-term and long-term safety of incorporating Y03501 into their feeding regimens. Moreover, independent evaluations by veterinary experts and feed safety authorities endorse its use, further attesting to its reliability and safety.

What animals benefit the most from Y03501 Recombinant Human R-Spondin1?

While Y03501 Recombinant Human R-Spondin1 can potentially benefit a wide range of livestock, it is particularly effective in monogastric animals like pigs and poultry. These animals have a single-chambered stomach, making their digestive systems more straightforward and more directly influenced by enhancements in nutrient absorption efficiency. In pigs, for example, improved gut health facilitated by R-Spondin1 can lead to better weight gain and feed conversion ratios, key parameters for assessing productivity. In poultry, the benefits might include faster growth rates and stronger bones, owing to better nutrient absorption and utilization. Ruminants like cattle and sheep can also benefit, but the mechanisms may be slightly different due to their complex digestive systems involving multiple stomach chambers.

How is Y03501 Recombinant Human R-Spondin1 administered in animal feed?

Y03501 Recombinant Human R-Spondin1 is typically mixed directly into animal feed at specified concentrations to ensure uniform distribution and consistent intake. It can come in various formulations, including powders or liquids, making it versatile for different types of feed. The recommended dosage will vary depending on the type of animal and the specific goals of the feeding program (e.g., growth enhancement, gut health improvement). It is essential to follow the guidelines provided by the manufacturer to optimize benefits and ensure the safety of the animals. Mixability and stability studies ensure that R-Spondin1 remains effective throughout the feed’s shelf life, providing continuous benefits to the animals.

What research backs the efficacy of Y03501 Recombinant Human R-Spondin1?

Numerous scientific studies have been conducted to demonstrate the efficacy of Y03501 Recombinant Human R-Spondin1. Research published in peer-reviewed journals highlights its role in enhancing the Wnt signaling pathway, which leads to increased stem cell activity in the gut. This, in turn, results in better nutrient absorption and overall improved animal growth. Studies conducted on various livestock, including pigs, chickens, and cattle, have shown consistent results in terms of weight gain, feed conversion ratios, and health markers. Additionally, field trials in commercial farming environments have corroborated these findings, offering real-world evidence of its benefits. Detailed experimental methodologies and controls used in these studies also underscore the robustness and replicability of the research findings.

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