Synonym: Noggin
Species: Human
Protein Accession: P19012
Purity: Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level: Less than 1 EU/μg of Noggin as determined by LAL method
Biological Activity: The ED50 for this effect is typically 1-5 μg/mL
Expression System: E. coli
Fusion Tag: None
Predicted Molecular Mass: Approximately 26.5 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA
Reconstitution: Centrifuge vial before opening. Reconstitute in PBS, pH 7.4 to a
concentration of 0.1-1.0 mg/mL.
Storage & Stability: Store at -20°C upon receipt. Stable for up to 12 months at
-20°C.
FAQ
What is Y03301 Recombinant Human Noggin and how can it benefit the feed
industry?
Y03301 Recombinant Human Noggin is a bioengineered protein that
inhibits Bone Morphogenetic Proteins (BMPs), involved in various developmental and
homeostatic processes. In the feed industry, especially for livestock and poultry, the
inclusion of Y03301 has the potential to promote substantial growth and improve overall
health. By mitigating the influences of BMPs, it can encourage more efficient
utilization of nutrients and enhance cellular activities vital for growth. This can
translate into better bone density, more muscle mass, and a general increase in the
growth rate of animals. Farms can thus maintain a healthier stock, potentially reducing
the need for excessive feed and lowering mortality rates among younger
animals.
How does the inclusion of Y03301 Recombinant Human Noggin in animal feed
improve the growth and health of livestock?
Y03301 Recombinant Human Noggin works
by inhibiting BMP signaling pathways, which are responsible for bone and tissue
formation. By doing so, it creates a more favorable environment for anabolic processes,
especially in muscle and bone tissues. For livestock, this means a more robust growth
phase characterized by increased muscle fiber development and stronger bone formation.
Animals receiving Y03301 tend to convert food more efficiently, leading to better weight
gain without the need for increased feed. Additionally, improved bone health reduces the
instances of bone-related injuries and illnesses, contributing to overall well-being and
productivity of the livestock.
What types of animals can benefit from Y03301
Recombinant Human Noggin supplementation?
Y03301 Recombinant Human Noggin
supplementation is versatile and can be beneficial across various types of livestock
including cattle, swine, poultry, and even aquaculture species like fish and shrimp. For
each species, it supports critical growth phases by regulating and optimizing the
utilization of nutrients. For instance, in poultry, it can lead to stronger bone
formation and better muscle mass, which are crucial for commercial meat production. In
cattle and swine, stronger bones and more efficient protein synthesis due to regulated
BMP activity can lead to increased meat yield, improved overall health, and potentially
lower veterinary costs due to a reduction in bone-related injuries.
Are there any
potential side effects or risks associated with the use of Y03301 Recombinant Human
Noggin in animal feed?
While Y03301 Recombinant Human Noggin has shown promising
benefits in growth and health, it’s important to adhere to recommended dosages and use
guidelines set by regulatory authorities to avoid potential side effects.
Over-supplementation could disrupt normal biological processes because BMP signaling is
crucial for various physiological functions. Potential risks could include imbalances in
bone and tissue development or interference with other metabolic pathways. However, when
used correctly, it predominantly facilitates improved growth and health outcomes in
animals. Ongoing research and field studies continue to monitor its long-term effects to
ensure its safe and effective use in the feed industry.
How can the
implementation of Y03301 Recombinant Human Noggin improve the efficiency of feed
utilization?
The application of Y03301 Recombinant Human Noggin in animal feed
enhances feed efficiency by promoting better nutrient absorption and utilization. By
inhibiting BMPs that can otherwise slow down growth, Noggin allows for a more anabolic
state, encouraging faster and more efficient protein synthesis and bone development.
This results in animals requiring less feed to achieve the same or improved levels of
growth, which translates into reduced feed costs and increased productivity for farms.
Efficient feed utilization also minimizes waste, contributing to more sustainable
farming practices.