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Y03301 Recombinant Human Noggin

Synonym: Noggin

Species: Human

Protein Accession: P19012

Purity: Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level: Less than 1 EU/μg of Noggin as determined by LAL method

Biological Activity: The ED50 for this effect is typically 1-5 μg/mL

Expression System: E. coli

Fusion Tag: None

Predicted Molecular Mass: Approximately 26.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA

Reconstitution: Centrifuge vial before opening. Reconstitute in PBS, pH 7.4 to a concentration of 0.1-1.0 mg/mL.

Storage & Stability: Store at -20°C upon receipt. Stable for up to 12 months at -20°C.

FAQ

What is Y03301 Recombinant Human Noggin and how can it benefit the feed industry?

Y03301 Recombinant Human Noggin is a bioengineered protein that inhibits Bone Morphogenetic Proteins (BMPs), involved in various developmental and homeostatic processes. In the feed industry, especially for livestock and poultry, the inclusion of Y03301 has the potential to promote substantial growth and improve overall health. By mitigating the influences of BMPs, it can encourage more efficient utilization of nutrients and enhance cellular activities vital for growth. This can translate into better bone density, more muscle mass, and a general increase in the growth rate of animals. Farms can thus maintain a healthier stock, potentially reducing the need for excessive feed and lowering mortality rates among younger animals.

How does the inclusion of Y03301 Recombinant Human Noggin in animal feed improve the growth and health of livestock?

Y03301 Recombinant Human Noggin works by inhibiting BMP signaling pathways, which are responsible for bone and tissue formation. By doing so, it creates a more favorable environment for anabolic processes, especially in muscle and bone tissues. For livestock, this means a more robust growth phase characterized by increased muscle fiber development and stronger bone formation. Animals receiving Y03301 tend to convert food more efficiently, leading to better weight gain without the need for increased feed. Additionally, improved bone health reduces the instances of bone-related injuries and illnesses, contributing to overall well-being and productivity of the livestock.

What types of animals can benefit from Y03301 Recombinant Human Noggin supplementation?

Y03301 Recombinant Human Noggin supplementation is versatile and can be beneficial across various types of livestock including cattle, swine, poultry, and even aquaculture species like fish and shrimp. For each species, it supports critical growth phases by regulating and optimizing the utilization of nutrients. For instance, in poultry, it can lead to stronger bone formation and better muscle mass, which are crucial for commercial meat production. In cattle and swine, stronger bones and more efficient protein synthesis due to regulated BMP activity can lead to increased meat yield, improved overall health, and potentially lower veterinary costs due to a reduction in bone-related injuries.

Are there any potential side effects or risks associated with the use of Y03301 Recombinant Human Noggin in animal feed?

While Y03301 Recombinant Human Noggin has shown promising benefits in growth and health, it’s important to adhere to recommended dosages and use guidelines set by regulatory authorities to avoid potential side effects. Over-supplementation could disrupt normal biological processes because BMP signaling is crucial for various physiological functions. Potential risks could include imbalances in bone and tissue development or interference with other metabolic pathways. However, when used correctly, it predominantly facilitates improved growth and health outcomes in animals. Ongoing research and field studies continue to monitor its long-term effects to ensure its safe and effective use in the feed industry.

How can the implementation of Y03301 Recombinant Human Noggin improve the efficiency of feed utilization?

The application of Y03301 Recombinant Human Noggin in animal feed enhances feed efficiency by promoting better nutrient absorption and utilization. By inhibiting BMPs that can otherwise slow down growth, Noggin allows for a more anabolic state, encouraging faster and more efficient protein synthesis and bone development. This results in animals requiring less feed to achieve the same or improved levels of growth, which translates into reduced feed costs and increased productivity for farms. Efficient feed utilization also minimizes waste, contributing to more sustainable farming practices.

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