Synonym: Y01601
Species: Human
Protein Accession: Uniprot ID: Q02297
Purity: Greater than 95% as determined by SDS-PAGE
Endotoxin Level: Less than 1 EU/μg
Biological Activity: Fully biologically active when compared to standard.
Expression System: E. coli
Fusion Tag: None
Predicted Molecular Mass: The predicted molecular weight is approximately 7.8 kDa.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution: We recommend that this vial be briefly centrifuged prior to
opening to bring the contents to the bottom. Reconstitute in sterile distilled water or
aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Storage & Stability: Store at -20°C. Please prevent freeze-thaw cycles.
FAQ
What is Y01601 Recombinant Human Heregulinβ-1 (NRG1)?
Y01601 Recombinant Human
Heregulinβ-1 (NRG1) is a bioengineered protein that mimics the naturally occurring
heregulin (neuregulin-1) in animals. Heregulin belongs to the epidermal growth factor
(EGF) family and plays an essential role in cell proliferation, differentiation, and
survival. This recombinant version is designed to enhance various physiological
functions, particularly in livestock, by promoting muscle growth, improving nutrient
absorption, and strengthening immunity. Such properties make it an innovative additive
for the feed industry, aiming to boost animal productivity and overall
health.
How does Y01601 Recombinant Human Heregulinβ-1 (NRG1) work in
animals?
Y01601 operates through the activation of specific cell receptors known as
ErbB or HER receptors, primarily ErbB2, ErbB3, and ErbB4. When heregulin binds to these
receptors, it triggers a cascade of intracellular signaling pathways, including the
PI3K/Akt and MAPK pathways. These pathways promote cellular processes such as growth,
division, and survival. In livestock, this results in accelerated muscle growth,
enhanced feed efficiency, and better immune responses. Therefore, incorporating NRG1
into animal feed can significantly improve the overall performance and health of the
animals.
What benefits does Y01601 Recombinant Human Heregulinβ-1 (NRG1) offer in
animal feed?
Y01601 offers several advantages when used as an additive in animal
feed. Firstly, it enhances muscle growth and feed efficiency, leading to increased
weight gain and improved meat quality in livestock. Secondly, it improves nutrient
absorption and metabolism, ensuring that animals make better use of the feed they
consume. Thirdly, NRG1 can bolster the immune system, making animals more resilient to
diseases and reducing the need for antibiotics. Lastly, it promotes overall well-being,
decreasing stress and enhancing recovery times, which contribute to better animal
welfare and productivity.
How should Y01601 Recombinant Human Heregulinβ-1 (NRG1)
be administered in animal feed?
The administration of Y01601 should follow specific
guidelines to ensure optimal performance and safety. It is typically mixed directly into
the feed at a concentration determined by a series of trials and based on the species,
age, and weight of the livestock. The dosage must be carefully calibrated to achieve the
desired effects without causing any adverse reactions. It's recommended to consult with
a veterinary expert or a feed specialist to determine the suitable amount and
administration method for a particular farming setup. Proper storage conditions should
be maintained to preserve the protein's stability and efficacy.
Are there any
safety concerns or side effects associated with Y01601 Recombinant Human Heregulinβ-1
(NRG1) in animal feed?
Y01601 is generally considered safe when used according to
established guidelines. However, as with any feed additive, it is crucial to monitor
animals for any potential adverse reactions. Common safety checks involve monitoring the
health and behavior of the livestock to ensure there are no signs of toxicity or stress.
There have been no significant reports of negative side effects when used correctly.
Nonetheless, ongoing research and field trials are essential to continually assess its
safety profile. As always, it is advisable to consult with veterinary professionals to
ensure the safe and effective use of Y01601 in animal feed.