Synonym: Fibronectin
Species: Human
Protein Accession: Y01344
Purity: Greater than 95%
Endotoxin Level: Less than 1 EU/µg
Biological Activity: Supports cell adhesion and spreading
Expression System: Human Embryonic Kidney cells (HEK293)
Fusion Tag: None
Predicted Molecular Mass: Approximately 250 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution in phosphate buffered
saline (PBS)
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in sterile PBS,
pH 7.4 to a concentration of 0.1-1.0 mg/ml
Storage & Stability: Store lyophilized protein at -20°C. Aliquot reconstituted
protein and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
FAQ
How does Y01344 Recombinant Human Fibronectin benefit the feed industry?
Y01344
Recombinant Human Fibronectin holds significant promise for the feed industry due to its
bioactive properties. Fibronectin is a high-molecular-weight glycoprotein found in the
extracellular matrix of animal tissues, known for its role in cell adhesion, growth, and
differentiation. When incorporated into animal feed, it can promote healthier gut
environments, enhance nutrient absorption, and improve overall animal health.
One
major benefit of Y01344 is its ability to strengthen the intestinal barrier. This
glycoprotein can bind to cell surfaces, promoting the formation of a more robust
intestinal lining. A healthier gut lining means fewer pathogens and toxins can
penetrate, which reduces the likelihood of infections and diseases. Consequently,
animals are healthier, and the need for antibiotics and other medications is reduced,
aligning with the industry's move towards more sustainable and natural feed
solutions.
Furthermore, fibronectin supports cellular functions related to growth
and repair. When animals have enhanced cellular processes, they tend to gain weight more
efficiently and recover more quickly from injuries or stressors. This can lead to
improved feed conversion ratios (FCR) and better overall productivity, benefiting
producers economically.
In summary, incorporating Y01344 Recombinant Human
Fibronectin into animal feed can enhance gut health, reduce disease incidence, and
promote better growth rates, offering significant advantages in terms of both animal
wellness and operational efficiency.
Is Y01344 Recombinant Human Fibronectin safe
for animals?
Yes, Y01344 Recombinant Human Fibronectin is considered safe for
animal consumption when used according to recommended guidelines. The product is
bioengineered to mimic the naturally occurring fibronectin found in animal tissues,
ensuring it is biocompatible and functional within animal systems.
The
recombinant nature of this product means it is produced in a controlled environment,
which minimizes the risk of contaminants and ensures batch-to-batch consistency. This
high level of control in production also means that specific functional domains of
fibronectin critical for its bioactive properties are preserved and optimized for
safety.
Moreover, extensive studies and tests are conducted to ensure that Y01344
meets the safety and efficacy standards set by regulatory bodies before it is made
available to the market. These studies typically involve a range of animal species to
confirm that the product does not cause adverse reactions and delivers the anticipated
health benefits.
It's also important to note that fibronectin, as a component of
the extracellular matrix in all animal tissues, is a substance the animals' bodies
recognize and utilize effectively. This intrinsic compatibility means fewer risks of
allergic reactions or digestive issues compared to wholly foreign
compounds.
Thus, Y01344 Recombinant Human Fibronectin is a safe and natural
addition to the feed industry, supporting animal health in alignment with modern feed
safety standards.
How should Y01344 Recombinant Human Fibronectin be administered
in animal feed?
Administering Y01344 Recombinant Human Fibronectin in animal feed
involves several steps to ensure optimal efficacy and uniform distribution. The product
is typically provided in a powder or liquid form, making it easy to incorporate into
various feed formulations.
The first step is to determine the appropriate dosage
based on the type of animals being fed and their specific health or growth requirements.
Dosage recommendations are generally provided by the manufacturer or can be determined
in collaboration with veterinary or feed experts. Ensuring the right dosage is crucial
for maximizing benefits while maintaining safety.
Once the dosage is determined,
the fibronectin can be mixed with other feed ingredients. For dry feed formulations, the
powdered form of Y01344 should be uniformly blended with other dry components to ensure
even distribution. If utilizing the liquid form, it can be sprayed or mixed into the
feed to achieve similar uniformity. It's important to use proper mixing techniques to
avoid clumping and ensure each animal receives the intended dose.
In cases where
fibronectin is administered through liquid feed or water systems, it can be dissolved in
the drinking water. Consistent agitation or circulation of the water will help maintain
even dispersion and prevent settling. Monitoring water intake can provide additional
assurance that animals are receiving their intended fibronectin
supplementation.
Moreover, regular monitoring and adjustments based on animal
performance and health indicators are advisable. This iterative approach ensures animals
receive optimal benefits from fibronectin supplementation, taking into account variables
such as life stage, health status, and environmental conditions.
In summary,
Y01344 Recombinant Human Fibronectin should be administered with careful planning and
precision to maximize its benefits, taking into account proper dosage, mixing
techniques, and ongoing monitoring.
What types of animals can benefit from Y01344
Recombinant Human Fibronectin?
A wide range of animals within the feed industry
can benefit from Y01344 Recombinant Human Fibronectin due to its fundamental role in
cellular functions and overall health improvement. Livestock such as cattle, swine,
poultry, and even aquaculture species can experience enhanced health and productivity
when their diets are supplemented with this bioactive glycoprotein.
In cattle,
for example, fibronectin can improve gut health, which is particularly beneficial for
young calves and lactating cows. Healthier calves have better growth rates and lower
morbidity, reducing the incidence of costly treatments for diarrhea and other intestinal
ailments. For lactating cows, improved gut health leads to better nutrient absorption
and overall milk production quality.
Swine, particularly piglets, also stand to
gain significantly. Early-weaned piglets often face challenges such as gut immaturity
and increased susceptibility to infections. Supplementing their diets with Y01344 can
support the development of a stronger intestinal barrier and a balanced gut microbiota,
leading to improved growth rates and a reduction in post-weaning diarrhea.
In
poultry, fibronectin can support gut health and enhance immune function. Chickens,
turkeys, and other poultry species often face challenges with gut-related diseases that
can impact growth and feed efficiency. By integrating fibronectin into their feed,
producers can help reduce the prevalence of such diseases, leading to healthier flocks
and better overall productivity.
Aquaculture species, such as fish and shrimp,
can also benefit from fibronectin supplementation. Aquatic animals are often grown in
environments that can be stressful and prone to disease outbreaks. Enhancing their diet
with fibronectin can support gut health, improve resistance to infections, and promote
better feed conversion ratios, thus enhancing overall farm productivity.
In
essence, whether it's terrestrial or aquatic livestock, Y01344 Recombinant Human
Fibronectin has the potential to promote better health, growth, and productivity across
a wide spectrum of animals, making it a versatile and valuable addition to the feed
industry.
What are the economic benefits of using Y01344 Recombinant Human
Fibronectin in animal feed?
The economic benefits of incorporating Y01344
Recombinant Human Fibronectin into animal feed are multifaceted, offering significant
advantages to producers in terms of both cost savings and productivity gains. By
enhancing animal health and feed efficacy, fibronectin can lead to substantial
improvements in overall farm profitability.
One primary economic benefit is the
reduction in medical costs. Healthier animals have lower incidences of disease and
infections, which means fewer expenditures on antibiotics, veterinary services, and
other medical interventions. With diseases controlled, mortality rates decrease, leading
to more consistent and predictable production cycles.
Improved feed conversion
ratios (FCR) are another economic advantage. Fibronectin supports gut health and
nutrient absorption, meaning animals convert feed into body mass more efficiently.
Better FCR translates into lower feed costs per unit of weight gain, which can be
especially significant given that feed costs constitute a major portion of total
production expenses in the industry.
Enhanced growth rates and productivity also
result in faster turnaround times for livestock readiness. Animals achieve market weight
more quickly, thereby reducing the time and resources required for raising each batch.
This acceleration in growth cycles allows producers to increase their throughput and
overall output annually, improving revenue potential.
Another aspect is the
potential for premium product quality and market differentiation. Animals raised on
fibronectin-supplemented diets may exhibit better overall health, which can reflect in
the quality of meat, milk, or eggs produced. Superior product quality can command higher
market prices and create opportunities for branding and market positioning, offering a
competitive edge.
Additionally, by aligning with sustainability and antibiotic
reduction trends, producers can appeal to a growing segment of consumers concerned about
animal welfare and food safety. This alignment not only meets regulatory requirements
but also opens doors to new markets and potential premium pricing for feed
products.
In summary, the economic benefits of Y01344 Recombinant Human
Fibronectin extend beyond direct cost savings to include improved productivity, better
product quality, and market opportunities, making it a strategic investment for feed
industry stakeholders.