Synonym: EGF
Species: Human
Protein Accession: P01133
Purity: >95%
Endotoxin Level:
<0.1 ng/μg
Biological Activity: Determined by the dose-dependent stimulation of the
proliferation of EGF-responsive Balb/3T3 Cells
Expression System: E. coli
Fusion Tag: None
Predicted Molecular Mass: 6.2 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS
Reconstitution: Reconstitute in DMSO
Storage & Stability: Store at -20°C upon receipt, aliquot and store at
-20°C or -80°C. Avoid repeated freeze-thaw cycles.
FAQ
What is Y00801 Recombinant Human EGF, and how does it benefit the feed
industry?
Y00801 Recombinant Human Epidermal Growth Factor (EGF) is a
biotechnologically produced protein that plays a crucial role in cell growth,
proliferation, and differentiation. In the feed industry, it is primarily
utilized to promote improved growth rates and overall health in livestock,
poultry, and aquaculture. The benefits stem from EGF's ability to enhance
nutrient absorption, reinforce intestinal health, and mitigate the effects of
stress and disease. When introduced to animal feed, Y00801 stimulates the growth
and repair of epithelial tissues, leading to better nutrient uptake and energy
efficiency. This results in faster growth rates, higher feed conversion ratios,
and ultimately, increased productivity. Additionally, the consistent use of EGF
can reduce the need for antibiotics, thereby promoting a more sustainable and
eco-friendly farming practice.
How can Y00801 Recombinant Human EGF
improve feed conversion ratios in livestock?
EGF enhances feed conversion
ratios (FCR) by promoting the health and functionality of the gastrointestinal
tract. When the epithelial cells lining the gut are healthy and rapidly
regenerating, the animal can absorb nutrients more efficiently. This means that
more of the feed is converted into usable energy and growth rather than being
wasted. EGF's impact on cellular proliferation helps in maintaining optimal gut
health, reducing lesions, and fighting off pathogenic attacks, which commonly
hinder nutrient absorption. By ensuring a well-maintained gut lining, Y00801
minimizes nutrient loss and maximizes feed efficiency, thereby improving overall
FCR. This translates to reduced feed costs and better growth performance, making
livestock production more cost-effective and efficient.
Are there any
specific animals that benefit more from Y00801 Recombinant Human EGF
supplementation?
While Y00801 has shown positive effects across various
species, certain animals may exhibit more pronounced benefits due to their
unique physiology and growth patterns. In broiler chickens, for instance, EGF
supplementation can significantly shorten the growth cycle, allowing for quicker
turnover and higher yield. In swine, especially during weaning periods, the
introduction of EGF can mitigate the stress-related reduction in growth rates.
Aqua-farming species, like fish and shrimp, also greatly benefit from EGF as it
improves their ability to fight off common diseases and enhances overall growth
rates. Dairy cattle can see improvements in milk production and quality due to
better nutrient uptake and overall health. Therefore, while beneficial to a wide
range of animals, the most noteworthy impacts are observed in rapidly growing
and high-stress species like poultry, swine, and aquaculture.
What dosage
of Y00801 Recombinant Human EGF is recommended for optimal results?
The
optimal dosage of Y00801 Recombinant Human EGF varies depending on the species,
age, and specific needs of the animals being fed. For poultry, recommended
dosages usually range between 0.1 to 0.3 mg/kg of feed. In swine, particularly
during the weaning phase, dosages may be slightly higher, around 0.2 to 0.5
mg/kg of feed. For aquaculture, the dosages also fall within a similar range,
generally between 0.1 to 0.4 mg/kg of feed. It's important to conduct controlled
trials and monitor animal response to fine-tune the dosage according to specific
requirements. Over-supplementation can lead to diminishing returns or potential
negative effects, so adherence to recommended guidelines and close observation
is crucial. Consulting with a veterinary nutritionist can provide more precise
dosage tailored to specific livestock conditions and objectives.
Are
there any side effects or considerations when using Y00801 Recombinant Human EGF
in animal feed?
Generally, Y00801 Recombinant Human EGF is considered safe
when used at recommended dosages, but like any feed additive, it is important to
observe the animals for any adverse reactions when introducing it for the first
time. In rare cases, over-supplementation can lead to hyper-proliferation of
cells, which might cause gut imbalances or unexpected growth anomalies. It is
also crucial to maintain a balanced diet; EGF should not replace essential
nutrients but rather complement them to enhance overall growth and health.
Regular monitoring and consultation with veterinary professionals can ensure
that the supplementation is done correctly and adjustments are made as
necessary. Since this is a novel supplement, it’s advisable to stay updated with
ongoing research and field studies that might provide new insights into its
long-term effects and optimal usage strategies.