Synonym: C02402
Species: Human
Protein Accession: Uniprot P08637
Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Endotoxin Level: Less than 1 EU/ug as determined by LAL method.
Biological Activity: The antibody binds to human CD16 with high affinity and
blocks binding of IgG to CD16-expressing cells.
Expression System: CHO cells
Fusion Tag: Fc region of human IgG1
Predicted Molecular Mass: Approximately 147 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
Reconstitution: Reconstitute the lyophilized antibody in sterile deionized water
to a concentration of 0.1-1.0 mg/ml.
Storage & Stability: Store at -20°C. Stability is >2 years.
FAQ
What is C02402 Recombinant Anti-Human CD16 mAb, and how can it benefit the feed
industry?
C02402 Recombinant Anti-Human CD16 mAb is an innovative monoclonal
antibody specifically designed to target the CD16 antigen found on natural killer (NK)
cells and certain other immune cells, facilitating immune modulation. In the feed
industry, leveraging such advanced biotechnology can significantly improve animal health
and productivity. By enhancing the animals' immune function, this monoclonal antibody
can help mitigate the impact of infectious diseases, which are a significant concern in
livestock production. Healthier animals are more efficient in converting feed into body
mass, leading to better growth rates and higher yields of meat, milk, or eggs. Moreover,
reducing disease incidence through immune modulation decreases the reliance on
antibiotics, addressing public health concerns about antibiotic resistance. Thus, C02402
Recombinant Anti-Human CD16 mAb offers a promising avenue for optimizing animal welfare
and feed efficiency in a sustainable manner.
How does the C02402 Recombinant
Anti-Human CD16 mAb aid in disease prevention in livestock?
This monoclonal
antibody works by enhancing the activity of NK cells, which play a critical role in the
body's first line of defense against infections. By targeting and activating CD16
receptors, C02402 helps augment the animals' immune response, improving their ability to
fight off pathogens. In the feed industry, this translates to a more resilient livestock
population that can withstand infections more effectively. Enhanced immune function
lowers morbidity and mortality rates, ensuring that a higher percentage of animals reach
market weight, leading to better overall productivity. Furthermore, the improved health
of the animals often results in better feed conversion ratios, as healthy animals
utilize feed more efficiently. Integrating C02402 into feed programs can thus reduce the
economic burden of disease outbreaks and associated treatments, making it a valuable
tool for enhancing herd or flock health.
Can C02402 Recombinant Anti-Human CD16
mAb replace antibiotics in animal husbandry?
While C02402 can significantly
reduce the need for antibiotics by bolstering the animals' natural immune defenses, it
is not an outright replacement for antibiotics. Antibiotics are still necessary for
treating bacterial infections when they occur. However, the proactive use of this
monoclonal antibody can lower the incidence of such infections, thereby decreasing the
overall dependence on antibiotics. This is particularly crucial given the growing
concern over antibiotic resistance and its implications for both animal and human
health. By integrating C02402 into regular feeding practices, farmers can adopt a more
preventive approach to disease management, which aligns with best practices for
sustainable agriculture. Therefore, while C02402 does not replace antibiotics entirely,
it significantly complements and enhances current disease prevention strategies in the
feed industry.
What are the potential economic benefits of using C02402
Recombinant Anti-Human CD16 mAb in livestock production?
The use of C02402 in
livestock production offers several economic advantages. First, by reducing the
incidence of disease, the antibody helps lower veterinary costs associated with
treatments and interventions. Healthier animals also demonstrate better growth rates and
feed conversion efficiency, meaning that less feed is required to achieve the desired
weight gain, which translates to lower feed costs. Additionally, enhanced animal health
often results in lower mortality rates, ensuring a larger proportion of livestock
reaches market, thereby increasing revenue. Moreover, the reduction in antibiotic usage
can lead to fewer regulatory hurdles and potential market advantages, as consumers
increasingly seek products from antibiotic-free systems. By investing in the health and
immune function of their animals through C02402, farmers can see significant returns in
terms of both cost savings and income generation, making it a financially prudent
choice.
Are there any safety concerns associated with the use of C02402
Recombinant Anti-Human CD16 mAb in animals?
C02402 Recombinant Anti-Human CD16
mAb is designed with safety and efficacy in mind. Extensive pre-clinical studies and
field trials are typically conducted to ensure that the antibody does not have adverse
effects on animal health or product quality. As with any biological intervention,
monitoring and adhering to recommended usage guidelines is crucial to mitigate any
potential risks. Ensuring the correct dosage and administration is important to achieve
the desired immunomodulatory effects without overstimulating the immune system. Regular
veterinary oversight can further enhance safety, ensuring that any unforeseen reactions
are promptly addressed. Overall, when used as directed, C02402 has a favorable safety
profile, offering a reliable means to boost immune function and overall animal health
without compromising safety.