Synonym: C02302 mAb
Species: Human
Protein Accession: P10717
Purity: ≥95%
Endotoxin Level:
<1 EU/μg
Biological Activity: The antibody has been tested for flow cytometry
analysis, and it binds to human CD28 with high affinity and specificity.
Expression System: CHO cells
Fusion Tag: None
Predicted Molecular Mass: Approximately 150 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS
Reconstitution: Reconstitute with sterile distilled water
Storage & Stability: Store lyophilized product at -20°C. Once
reconstituted, store at 4°C for up to two weeks or aliquot and store at -20°C.
FAQ
What is C02302 Recombinant Anti-Human CD28 mAb and what are its applications in
the feed industry?
C02302 Recombinant Anti-Human CD28 monoclonal antibody
(mAb) is a highly specialized antibody designed to bind specifically to the CD28
molecule present on the surface of T cells. In the context of the feed industry,
this antibody finds its primary application in the modulation of the immune
response of animals. By targeting CD28, it can enhance or suppress the immune
signaling pathways, thereby improving animal health and productivity. This
capability is crucial in managing infections and inflammatory conditions that
farm animals may encounter. Additionally, enhancing the overall immune function
of livestock can result in better nutrient absorption and growth performance,
leading to more efficient and sustainable agricultural practices.
How
does C02302 Recombinant Anti-Human CD28 mAb improve animal health?
C02302
Recombinant Anti-Human CD28 mAb aids in improving animal health by modulating
the immune response. The binding of this monoclonal antibody to CD28 on T cells
can activate these cells, leading to a more robust immune response against
pathogens. This heightened immune surveillance can effectively reduce the
incidence of infectious diseases, thus minimizing the need for antibiotics and
other medications. Enhanced T cell activity can also lead to better handling of
vaccinations, resulting in stronger and longer-lasting immunity. Healthier
animals demonstrate improved weight gain, feed conversion ratios, and overall
productivity, making this antibody a valuable tool for livestock management in
the feed industry.
Is there any evidence supporting the effectiveness of
C02302 Recombinant Anti-Human CD28 mAb in livestock?
Yes, there is
evidence supporting the effectiveness of C02302 Recombinant Anti-Human CD28 mAb
in improving the health and productivity of livestock. Research studies and
trials have demonstrated that animals treated with this monoclonal antibody show
significant improvements in immune parameters, leading to better disease
resistance. These studies often measure outcomes such as reduced mortality
rates, lower incidence of infections, and improved weight gain and feed
efficiency. Moreover, field applications in farm settings have replicated these
results, validating the antibody's efficacy in real-world conditions. The
consistent positive outcomes emphasize the mAb's potential as a reliable
immunomodulatory agent in animal husbandry.
Are there any safety concerns
associated with the use of C02302 Recombinant Anti-Human CD28 mAb in
animals?
The safety profile of C02302 Recombinant Anti-Human CD28 mAb has
been extensively evaluated to ensure its suitability for use in animals.
Preclinical studies, including toxicology assessments and long-term exposure
tests, have been conducted to address potential safety concerns. These studies
have shown that the antibody is well-tolerated at the recommended doses, with
minimal or no adverse effects observed in treated animals. However, it is
essential to follow the recommended usage guidelines and monitor animals for any
unexpected responses. As with any new therapeutic agent, continued vigilance and
reporting of any adverse effects are crucial for maintaining safety and
efficacy.
How does the cost-benefit analysis of using C02302 Recombinant
Anti-Human CD28 mAb compare with traditional methods of immune enhancement in
the feed industry?
The cost-benefit analysis of using C02302 Recombinant
Anti-Human CD28 mAb often shows favorable outcomes when compared with
traditional methods of immune enhancement. While the initial investment in
monoclonal antibodies may be higher than conventional treatments like
antibiotics or feed additives, the long-term benefits can outweigh these costs.
Enhanced immune function leads to healthier animals, reducing expenses related
to veterinary care and medication. Improved growth rates and feed conversion
efficiency result in higher productivity and profitability. Additionally, the
reduction in antibiotic use aligns with regulatory trends and consumer
preferences, potentially opening new market opportunities. These factors
collectively enhance the economic viability of incorporating this antibody into
livestock management practices.