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Y04001Recombinant Human IL-12

Synonym: IL-12, NKSF, Cytotoxic lymphocyte maturation factor 2 (CLMF2), p70

Species: Human

Protein Accession: P29460

Purity: ≥95%

Endotoxin Level: <0.1 ng per µg of protein

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human NK cells is less than 0.5 ng/ml, corresponding to a specific activity of >2.0x106 IU/mg.

Expression System: HEK 293 cells

Fusion Tag: None

Predicted Molecular Mass: 21.5 kDa

Formulation: Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH7.0

Reconstitution: It is recommended to reconstitute the lyophilized recombinant Human IL-12 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Storage & Stability: Store lyophilized recombinant Human IL-12 at -20°C. It is stable for up to 12 months from date of receipt when stored at -20°C to -80°C. Reconstituted IL-12 should be stored in working aliquots at -20°C.

FAQ

What is Y04001 Recombinant Human IL-12 and how does it benefit the feed industry?

Y04001 Recombinant Human IL-12 is a synthetic form of the naturally occurring interleukin-12 (IL-12) protein. IL-12 is a cytokine that plays a significant role in the immune response by enhancing the functionality of T-cells and natural killer (NK) cells. In the feed industry, utilizing Y04001 Recombinant Human IL-12 can markedly improve animal health and productivity. Its immune-boosting properties can help in reducing the prevalence of diseases, thereby minimizing the need for antibiotics. This approach supports the trend towards antibiotic-free meat production, meeting consumer demand for safer and more natural animal products. Additionally, healthier animals tend to exhibit better growth rates and feed conversion efficiency, resulting in economic benefits for farmers and producers.

How is Y04001 Recombinant Human IL-12 administered to animals in the feed industry?

Y04001 Recombinant Human IL-12 can be administered in several ways to ensure its effectiveness and ease of use within the feed industry. One common method is incorporation into feed or water, allowing for easy mass administration without the need for individual handling. This method ensures that all animals receive the cytokine consistently, enhancing overall herd health. Alternatively, it can be administered via injectable formulations for targeted therapy in high-risk scenarios or to individual animals that require immediate immune support. Adapting the mode of administration to the specific needs of the production system can optimize the benefits of Y04001 Recombinant Human IL-12, making it a versatile tool for enhancing animal welfare and production efficiency.

Are there any safety concerns associated with the use of Y04001 Recombinant Human IL-12 in animal feed?

The use of Y04001 Recombinant Human IL-12 in animal feed is generally considered safe, provided it is used according to recommended guidelines and dosages. Extensive research and testing are conducted to ensure that recombinant cytokines like IL-12 do not pose toxicity risks to animals or humans who might consume the animal products. Regulatory agencies evaluate these products rigorously before approval for use in the feed industry. Potential side effects are usually minimal and may include temporary changes in animal behavior or mild inflammatory responses, which are often indicative of the immune system activation desired by the product. Routine monitoring and adherence to recommended usage protocols can mitigate most safety concerns, ensuring that the benefits of IL-12 are harnessed effectively.

Can Y04001 Recombinant Human IL-12 be used in combination with other feed additives or medications?

Yes, Y04001 Recombinant Human IL-12 can be used in combination with other feed additives or medications. Its primary role is to enhance the animal's immune response, making it complementary to other health and nutrition interventions rather than conflicting with them. When used alongside probiotics, vitamins, and essential minerals, it can provide a comprehensive approach to animal health. Additionally, Y04001 Recombinant Human IL-12 can reduce reliance on antibiotics by boosting natural immunity, promoting a healthier gut microbiome when combined with prebiotics or probiotics. However, it is crucial to consult with a veterinarian or animal nutritionist to ensure optimal combinations and dosing schedules that maximize the effectiveness and safety of the feed regimen.

How does Y04001 Recombinant Human IL-12 improve animal welfare and productivity?

Y04001 Recombinant Human IL-12 significantly enhances animal welfare and productivity by strengthening their immune systems, which leads to reduced incidence of diseases and infections. As animals become less susceptible to illnesses, there is a marked improvement in their overall health and well-being. This leads to a decrease in mortality rates and less need for medical interventions, which can be stressful for animals. Healthier animals exhibit better growth rates and feed conversion ratios, directly translating to increased productivity. Improved immune function also means animals are better equipped to handle stress, environmental changes, and other potential challenges in their living conditions. This comprehensive boost in health and welfare not only aligns with ethical farming practices but also supports economic gains through improved product quality and quantity.

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