Synonym: FGF-basic
Species: Human
Protein Accession: P09038
Purity: Greater than 95%
Endotoxin Level: Less than 1 EU/μg
Biological Activity: The ED50 as determined by a cell proliferation assay using
murine Balb/c 3T3 cells is less than 0.1 ng/mL.
Expression System: E. coli
Fusion Tag: None
Predicted Molecular Mass: Approximately 17.3 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 500mM NaCl,
pH 7.4
Reconstitution: Centrifuge vial before opening. Reconstitute in sterile distilled
water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL.
Storage & Stability: Store at -20°C. For maximum stability, store at -20°C or
below. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or
BSA). Please avoid repeated freeze-thaw cycles.
FAQ
What is Y00321-Recombinant Human Heat Stable bFGF and how can it benefit the feed
industry?
Y00321-Recombinant Human Heat Stable Basic Fibroblast Growth Factor
(bFGF) is a biotechnologically engineered version of the naturally occurring bFGF
protein, designed for enhanced stability under high-temperature conditions. In the feed
industry, this product offers numerous benefits. Firstly, it promotes cellular
proliferation and wound healing, which is vital for the health and growth of livestock.
By facilitating the regeneration of tissues, bFGF can help in reducing recovery times
after injuries or illnesses, ensuring livestock remain healthy and
productive.
Moreover, by enhancing the overall health of livestock, bFGF reduces
the reliance on antibiotics and other medications, fostering a more sustainable and
organic approach to animal husbandry. Additionally, incorporating heat-stable bFGF in
feed products helps maintain its efficacy even after the pelleting process, which
involves high temperatures that typically denature proteins. This ensures that the
functional benefits of bFGF are retained, thus providing consistent growth and health
advantages to the animals consuming the feed.
How does the heat stability
feature of Y00321-Recombinant Human Heat Stable bFGF make it suitable for the feed
manufacturing process?
The heat stability feature of Y00321-Recombinant Human
Heat Stable bFGF is particularly critical for the feed manufacturing process because
feed production often involves high-temperature procedures, such as pelleting. Pelleting
increases feed density, improves handling characteristics, and enhances the nutritional
uniformity of the feed. However, the high temperatures required for pelleting can
denature sensitive proteins, rendering them inactive and ineffective.
The
heat-stable property of Y00321 means it can withstand these high temperatures without
losing its functional integrity. This ensures that the beneficial properties of the
bFGF, including promoting cell growth and aiding tissue repair, remain effective even
after the feed has been processed. Consequently, feed manufacturers can confidently
incorporate this growth factor into their products without worrying about thermal
degradation, ensuring that livestock receive the full spectrum of benefits from the
feed. This feature thus helps in maintaining the efficacy and nutritional value of feed,
leading to healthier and more productive livestock.
What specific benefits does
Y00321-Recombinant Human Heat Stable bFGF offer to livestock health and
productivity?
Y00321-Recombinant Human Heat Stable bFGF offers several specific
benefits that can significantly enhance livestock health and productivity. One of the
primary benefits is the promotion of cell proliferation, which is essential for growth
and tissue repair. This growth factor can accelerate wound healing and recovery from
injuries or illnesses, reducing downtime and increasing overall
productivity.
Additionally, bFGF can improve digestive health by promoting the
growth and repair of intestinal lining cells, enhancing nutrient absorption and overall
feed efficiency. This leads to better growth rates and improved feed conversion ratios,
which are critical for the economic performance of livestock operations.
Furthermore, bFGF also supports the immune system by stimulating the growth of
immune cells, thereby enhancing the animals' ability to fight off infections and
diseases. Healthier livestock means lower mortality rates and reduced veterinary costs,
further improving the profitability and sustainability of farming operations.
By
maintaining overall health and boosting productivity, Y00321-Recombinant Human Heat
Stable bFGF provides a multifaceted approach to improving livestock performance,
contributing to the success of the feed industry.
How do you incorporate
Y00321-Recombinant Human Heat Stable bFGF into animal feed, and are there any specific
dosage recommendations?
Incorporating Y00321-Recombinant Human Heat Stable bFGF
into animal feed is a straightforward process due to its stability under high
temperatures. The growth factor can be mixed into the feed during the formulation stage
before the pelleting process. Since its heat-stable properties protect it from
degradation, it remains effective even after the high-temperature conditions used during
feed pelleting.
As for dosage recommendations, the optimal amount of bFGF to be
included in the feed will depend on factors such as the type of livestock, their age,
weight, health status, and specific production goals. It is important to conduct trials
to determine the most effective concentration for your specific application. Generally,
guidelines provided by the manufacturer or results from scientific research can be used
as a starting point for dosage recommendations. It is advisable to consult with a
veterinarian or an animal nutritionist to tailor the dosage to meet the particular needs
of your livestock, ensuring that they receive the full benefits of Y00321-Recombinant
Human Heat Stable bFGF.
Are there any safety concerns or side effects associated
with the use of Y00321-Recombinant Human Heat Stable bFGF in animal
feed?
Y00321-Recombinant Human Heat Stable bFGF has been designed through
biotechnological processes to be safe for inclusion in animal feed. Extensive research
and trials are typically conducted to ensure that such ingredients are non-toxic,
non-allergenic, and effective for use in animal nutrition. However, like any new feed
ingredient, it is important to monitor livestock for any unusual reactions when first
introducing Y00321-Recombinant Human Heat Stable bFGF.
Potential side effects are
rare but could include hypersensitivity reactions in some animals. To mitigate any
risks, it is advisable to introduce the growth factor gradually and under the
supervision of a veterinarian. It is also critical to follow the recommended dosage
guidelines and not to exceed the specified amounts, as an overdose could potentially
lead to adverse effects.
Moreover, ensuring that the bFGF comes from a reputable
supplier that adheres to stringent quality control standards will help minimize any
safety concerns. Overall, when used as directed, Y00321-Recombinant Human Heat Stable
bFGF is considered a safe and beneficial addition to animal feed, promoting health and
productivity without significant safety risks.