Synonym: GM-CSF, Colony-stimulating factor, Multi-CSF, M-Csf
Species: Human
Protein Accession: P04141
Purity: ≥ 95%
Endotoxin Level:
< 1.0 EU per 1 μg of the protein
Biological Activity: The ED50 for this effect is typically 0.1-0.5 ng/mL
Expression System: E. coli
Fusion Tag: None
Predicted Molecular Mass: 14.1 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS
Reconstitution: It is recommended to reconstitute the lyophilized GM-CSF
in sterile 18 MΩ-cm H2O not less than 100 µg/ml, which can then be further
diluted to other aqueous solutions.
Storage & Stability: Store lyophilized protein at -20°C. Aliquot
reconstituted protein and store in working aliquots at -20°C to -70°C. Avoid
repeated freeze-thaw cycles.
FAQ
What is Y01501 Recombinant Human GM-CSF and how can it benefit the feed
industry?
Y01501 Recombinant Human Granulocyte-Macrophage
Colony-Stimulating Factor (GM-CSF) is a synthetic version of a naturally
occurring protein that plays a critical role in the immune system by stimulating
the production of white blood cells. In the feed industry, it offers significant
advantages by promoting the health and growth of livestock. Enhanced immune
responses reduce the risk of infections and diseases, leading to healthier
animals, less need for antibiotics, and improved overall productivity. These
effects can increase the yield and quality of meat, milk, and other animal
products, providing a substantial economic benefit to farmers and
producers.
How does Y01501 Recombinant Human GM-CSF function in the body
of livestock?
Y01501 Recombinant Human GM-CSF functions by binding to
specific receptors on the surface of hematopoietic cells, which are cells
involved in the formation of blood. This interaction stimulates the
proliferation and differentiation of various white blood cells such as
granulocytes, macrophages, and dendritic cells. An increase in these cell types
enhances the animal's ability to fight off infections, recover from illnesses
faster, and maintain a more robust immune system overall. Thus, incorporating
this cytokine into feed can lead to healthier livestock populations with
enhanced disease resistance.
Is Y01501 Recombinant Human GM-CSF safe for
all types of livestock?
Yes, Y01501 Recombinant Human GM-CSF is generally
safe for all types of livestock, including poultry, cattle, swine, and sheep. It
has been rigorously tested to ensure that it poses no harm to animals when used
according to recommended guidelines. Nonetheless, it’s crucial to follow
species-specific dosage and administration instructions to maximize benefits and
avoid any potential side effects. Always consult with a veterinarian or a
livestock nutritionist to customize the feeding program that includes this
cytokine, ensuring it suits the particular needs of the animals being
raised.
How can Y01501 Recombinant Human GM-CSF reduce the reliance on
antibiotics in livestock farming?
The incorporation of Y01501 Recombinant
Human GM-CSF into livestock feed can significantly bolster the animals' immune
systems, making them more resistant to infections and diseases. A robust immune
response means that animals are less likely to succumb to illnesses that would
typically require antibiotic treatment. Reducing the need for antibiotics is
beneficial not only for animal health and welfare but also helps in combatting
the global issue of antibiotic resistance. By minimizing antibiotic use,
producers can ensure healthier livestock and more sustainable farming
practices.
What are the economic implications of using Y01501 Recombinant
Human GM-CSF in animal feed for farmers and producers?
Using Y01501
Recombinant Human GM-CSF in animal feed can offer significant economic
advantages to farmers and producers. Healthier animals are more productive,
leading to higher yields of meat, milk, or eggs. Reduced disease incidence means
lower veterinary costs and less financial loss from livestock mortality.
Additionally, a reduced need for antibiotics can lower overall medical expenses
and align with consumer demand for antibiotic-free animal products, potentially
commanding higher market prices. These factors collectively drive profitability
while supporting more sustainable farming practices.